Progress in Pherine Medications
Pherin Pharmaceuticals, Inc. (Pherin) is exclusively focused on the development of pherines for the treatment of human diseases and disorders. To date, our technology has allowed us to make discoveries and file patents and patent applications that cover a large number of pherine molecules. Our broad pipeline of products includes four lead compounds: Aloradine™ IN for acute treatment of Social Anxiety Disorder; PH10 nasal spray for acute treatment of Depression; Salubrin™ HF NS, for acute management of Menopausal Hot Flashes and other symptoms of menopause; PH10 nasal spray for ; and PH15 nasal spray for Cognitive Improvement. Pherin holds worldwide marketing rights to these compounds. We are open to discussions of collaborative licensing opportunities with forward-looking and technologically innovative pharmaceutical companies.
The results of a Phase 2B clinical study and a recently completed Phase 3 Feasibility study show significant and rapid clinical efficacy, excellent safety and benefits of the product Aloradine NS for the acute treatment of the symptoms of Social Anxiety Disorder. Pherin also conducted a Phase 2A clinical study to investigate the dosing regimen, product profile and proof of concept of the product PH10 nasal spray for the acute and PRN treatment of Depression, and Salubrin-HF for the acute management of Menopausal Hot Flashes. Also completed is a Phase 2B clinical efficacy and safety study of PH80-PMD for the treatment of Premenstrual Dysphoric Disorder.
We believe the unique mechanism of action and method of delivery of pherines results in numerous therapeutic advantages.
Properties of Pherines
The term pherines refers to odorless substances that have pharmacological effect as a consequence of binding to specific peripheral receptors in the nasal passages.
Depression - Depression is a mood disorder characterized by extreme and persistent disruption of a person’s usual emotional state, affecting physical health as well as how the sufferer feels, thinks and behaves toward others.
Cognition Improvement - Cognitive deficits are characterized clinically by progressive loss of memory, cognition, reasoning, judgment and emotional stability that can gradually lead to profound mental deterioration.